Scientists at the laboratory are investigating how long-term biochemical stress contributes to cellular aging and tissue degeneration. Current studies focus on mitochondrial dysfunction, oxidative signaling imbalance, and cumulative protein instability. The research may contribute to future preventative therapies aimed at improving long-term cellular resilience and healthy aging.
The Alder Molecular Biochemistry Laboratory has joined an international consortium studying metabolic adaptations in aggressive tumor environments. Researchers aim to better understand how cancer cells alter biochemical pathways to survive under nutrient-limited conditions. The collaboration will support shared datasets, joint publications, and translational therapeutic development initiatives.
The laboratory has received new funding to support a multi-year research initiative examining metabolic dysfunction in obesity and Type 2 diabetes. Researchers will analyze how altered biochemical signaling pathways affect long-term cellular health and energy regulation. The project includes collaborations with clinical researchers and computational biologists to develop predictive metabolic models using large-scale molecular datasets.
Scientists at the Alder Molecular Biochemistry Laboratory have identified a previously uncharacterized enzyme involved in regulating oxidative stress responses within human cells. The discovery may improve understanding of how cells adapt to environmental and metabolic stress conditions associated with chronic disease progression. The research team is now investigating how modulation of the enzyme’s activity could […]